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… liraglutide, glimepiride, or insulin glargine U-100. After about five years, all four drugs improved blood glucose levels when added to metformin. Liraglutide and insulin glargine improved blood glucose levels slightly better than the others. However, nearly three of every four study participants were still unable … differences in the medications’ effects on blood glucose, heart disease, and other conditions. For instance, the liraglutide or insulin glargine groups maintained their target blood glucose …

… Getting enough physical activity can make both your body and mind feel better. It can also help prevent or delay health problems. Now, researchers are looking for ways to find out which exercises may best suit your body. Different types of exercise can … he says. His research team has identified a set of genes that predict who will get the biggest improvements in heart health from aerobic exercise, like jogging or cycling.  Bamman’s team has …

… happening in your body,” says NIH eye health expert Dr. Houmam Araj. It’s a convenient way for a doctor to get a clear view of your blood vessels, nerves, and connecting tissue without surgery. Researchers are working on new technologies to help doctors get a better look into the eye and catch diseases earlier. They’re also designing new tools to help … you will get them. New methods of detection and treatment can impact people everywhere.” … Improving “Sight” … New technologies may also help people with low vision and blindness get …

… they can take a big bite out of warm-weather fun. Bites from infected ticks are responsible for about a half-million new illnesses each year in the U.S. And those numbers are rising. Lyme … take steps to keep ticks from making you sick. And NIH-supported scientists are looking for better ways to diagnose, treat, and prevent tick-related illnesses. … Risks From Ticks … The … diseases at Yale University. He and his colleagues are working to better understand the relationships between ticks, the germs they carry, and the animals they infect. Ticks might seem …

… of DNA you inherit from your parents that defines features, like your risk for certain diseases.] that control the way our cells function. These changes affect how cells … Your genes, lifestyle, and environment all contribute to your risk. Researchers are trying to better understand how each plays a role. People with a family history of breast cancer are at … how cancer cells grow, divide, and spread. Targeted treatments for HER2-positive cancer have improved survival over the last decade. The most recent type of cancer treatment is called …

… to help you move throughout the day. NIH-funded studies of biomechanics have already led to better ways to prevent muscle and joint injuries in kids during sports and play, and to help … are working to develop better artificial joints. Others have devised improved treatments for movement disorders such as cerebral palsy and Parkinson’s disease. Joints are a common source …

… can lower blood pressure and improve sleep. It may even help people cope with pain. “For many chronic illnesses, mindfulness meditation seems to improve quality of life and reduce … Paying closer attention to your body can help you notice signals that you’re full and help you better enjoy your food. This body awareness seems to be one part of how mindfulness helps people … just about everybody feels better afterwards. So, with mindfulness training we’re aware of it improving our mood, and then we can use that reward to actually train ourselves,” Loucks says. …

… effects of a highly processed and a minimally processed diet in 10 men and 10 women residing for four weeks at the NIH Clinical Center. Each diet lasted for two weeks. People received three … to avoid. “Just telling people to eat healthier may not be effective for some people without improved access to healthy foods,” says NIH obesity expert Dr. Kevin Hall, who led the study. More studies are needed to better understand how processed food affects weight. …

… Is the long, cold winter getting you down? For people with seasonal affective disorder (SAD), the change in seasons brings on a form of … But experts caution that St. John’s wort can interact with many medications. And melatonin may improve sleep for some people with SAD, but it’s not known if long-term use is safe. If you’re experiencing SAD, talk with your doctor to come up with a plan to feel better. Learn more. …

… Spaces … Studies show that green spaces, such as parks or woods, seem to affect your health for the better. Dr. Francine Laden, an epidemiologist at the Harvard T.H. Chan School of Public Health, …